… , suppress apoptosis of oocytes and have a trend to elevate the meiotic-specific cohesin
subunits (REC8 and SMC1β) in oocytes of aged mice, indicating a beneficial effect on the …

… Abstract: The maturation quality of oocytes not only is the basis of mammalian reproductive
… Prevention of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in …

… Finally, the defects of maturation oocytes from aged mice and … Sirt3 prevents maternal
obesity-associated oxidative stress … on the regulation of mammalian oocyte meiosis resumption. …

… Results Totally 372 oocytes were obtained,179 oocytes from the young group and 193
oocytes from aged group. The abnormal rate of spindle of elderly mouse oocytes ( 71.78% ± 1.27…

… in oocytes, however the developmental capacity of oocytes carrying DNA damage is significantly
reduced. In clinical practice, aging… damage and repair in mammalian oocytes at various …

… Mammals synthesize polyamines de novo from amino acids or … reduce the rate of oocyte
aneuploidy and improve the embryonic … and material exchange between mother and fetal. This …

… Age-related reduction of SIRT2 levels in mammalian follicles … , which provides a new idea
for preventing oocyte aging. … Aging -related aneuploidy is associated with mitochondrial …

… Centrosome dynamics during mammalian oocyte maturation with a focus on meiotic … oocyte
pool and aneuploidy :a comparative study of the reproductive potential of young and aged …

… its effects on meiotic maturation of oocytes, … during oocyte maturation and subsequent
embryonic development. Blocking XRCC1 by microinjection with antibodies partly reduced oocyte …

… Towards a new understanding on the regulation of mammalian oocyte … Effects of reproductive
aging and postovulatory aging on the maintenance of biological competence after oocyte …