[HTML][HTML] NAD+/SIRT2 途径调节衰老卵母细胞成熟质量的分子机制

徐德军, 赵中权, 赵永聚 - 畜牧兽医学报, 2022 - xml-data.org
… 研究报道,SIRT2-BubR1是决定衰老卵母细胞核成熟事件的重要途径,衰老诱导的SIRT2蛋白
丢失… of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in mice by …

sirtuin 2 在炎症中的上下文依赖性作用

N Sola-Sevilla, M Garmendia-Berges… - 中国神经再生研究 …, 2025 - sjzsyj.com.cn
… In their article, they demonstrated that pharmacological inhibition of SIRT2 attenuates the
allergic asthmatic phenotype in mice after being sensitized and challenged with a triple-…

复杂疾病小鼠模型构建新策略: 类精子单倍体胚胎干细胞介导的半克隆技术

赖梭梅, 丁一夫, 李劲松 - 实验动物与比较医学, 2021 - slarc.org.cn
… after gene editing into oocytes, semi-cloned mice with a definitive genotype can be obtained
BubR1 insufficiency causes early onset of agingassociated phenotypes and infertility in mice