… accessibility at the single‑cell whole‑genome level, identification of cis‑regulatory elements,
and deciphering genetic … chromatin for fast and sensitive epigenomic profiling of open chro‑ …

… for studying the epigenetics and molecular mechanisms in … , identification of cis-regulatory
elements, and dissection of … dynamics of embryonic development at single-cell resolution. …

… of cis-regulatory factors or non-protein coding genes. In addition, a combination of
CRISPR/Cas9 screen and single cell … CRISPR-Cas9 epigenome editing enables high-throughput …

… of sequencing technology, a large number of omics sequencing technologies continue to
emerge and promote, resulting in a large number of omics data including genome, epigenome, …

… Overall, this study demonstrates the value of epigenetic data in fine-mapping functional
variants and provides a compendium of resources for further research on the epigenetics and …

… ) Single cell RNA sequencing is on the single cell level, of genome, transcriptome, and
epigenome … Cis-regulatory landscapes of four cell types of the retina. Nucleic Acids Res. 2017;45(…

… Functional characterization of the osteoarthritis genetic risk … CRISPR-based epigenome
editing of cytokine receptors for … , JD Single-cell and single-molecule epigenomics to uncover …

: 超级增强子是一类包含多个普通增强子的大簇, 主要富集高密度的转录因子, 辅助因子及增强子
相关表观修饰位点. 与普通增强子相比, 超级增强子具有更高的转录激活能力, 在细胞类型特异性…

… Characterization of three loci for homologous gene targeting and transgene expression[J]. …
A compendium and comparative epigenomics analysis of Cis-regulatory elements in the pig …

… Single-cell chromatin accessibility identifies pancreatic islet cell type- and state-specific …
Characterizing cisregulatory elements using single-cell epigenomics. Nat Rev Genet, 2022, …