The ContraCancrum project aims at developing a composite multilevel platform for
simulating malignant tumor development and tumor and normal tissue response to
therapeutic modalities and treatment schedules. The project aims at having an impact
primarily in (a) the better under-standing of the natural phenomenon of cancer at different
levels of biocomplexity and most importantly (b) the disease treatment optimization
procedure in the patient's individualized context by simulating the response to various …

ONTRACANCRUM [1-2] is developing a composite multilevel platform for simulating
malignant tumor development and tumor and normal tissue response to therapeutic
modalities and treatment schedules. The clinical validation of the models will be achieved by
dedicated clinicogenomic studies in gliomas and lung cancer. The results of the simulations
will be validated by the real outcome of treatment response using imaging studies. Tumor
tissues and blood samples of about 100 patients are being obtained from patients with lung …