… proteins experiment AS events at their PrLDs, generating isoforms with or without these domains, which critically … ) and two, one or none predictedintrinsicallydisordered regions (IDRs). …
孙灿壮, 冯永娥 - Hans Journal of Biomedicine, 2023 - hanspub.org
… , they perform critical biological functions in … disorderedproteins (IDPs). The results can provide a reference for further study of intrinsicallydisorderedproteins (IDPs) or intrinsically …
… long been established as an intrinsicallydisorderedprotein associated with a dysfunctional … The core sequence of the 9 imperfect repeats that predict α-helicity are shown in green font, …
… of our functional proteome is structurally disordered, either in the … protein with intrinsically disordered regions is estimated to constitute some 50% of our proteome. These are proteins …
… In this review, we first overview the history of the conventional … 的称呼有 多种: intrinsically disorderedproteins[5],natively un鄄 folded proteins[4],intrinsically unstructured proteins[6], 以及…
… risk prediction in patients affected by neurological disorders. … review the step-by-step process of data analysis, focusing on a selection of available tools and addressing the main critical …
… learning neural network to identify critical windows for individualized disease prediction; (4) … and accurate predictions of the intrinsic processes that culminate in neurodegeneration. …