… Conclusion The impaired intestinal barrier and increased intestinal permeability in UC … of P-glycoprotein in the colonic mucosa of ulcerative colitis patients and its clinical significance[J]. …
… 下自聚集导致的溶解度差,渗透性低,P-gp (P-glycoprotein) 介导的外排和肝肠代谢.提高小檗碱的 … permeability, P-glycoprotein (P-gp)-mediated efflux, and liver and intestinemetabolism. To …
… metabolism are the primary factors that limit the oral bioavailability of these natural products although chemical and microbial stability may also contribute … P-glycoprotein (P-gp). Human …
… P-gly coprotein expression and function in humans[ J] .Adv … The drug transporter P-glycoprotein limits oral absorption and … modulation of intestinal CYP3A metabolism by P-glycoprotein :…
… Low limit detection of cefaclor was 0 .1 mg·L -1 as a signal to … [ 12] , organic cation transport system [ 14] and P-glycoprotein-… :a mechanism contributing to poor oral absorption[ J] .…
… oral bioavailability and CNS accumulation of drugs[ J] .Int J … The drug transporter P-glycoprotein limits oral absorption and … induces intestinalP-glycoprotein MDR1 and intestinal and he…
SA Mousa, BM Ayoub - 中国神经再生研究(英文版), 2019 - sjzsyj.com.cn
… for P-glycoprotein, which not only limits the oral absorption … of cognition and neuronal function in brain. Neurodegenerative … Author contributions: All authors have equally contributed to …
… Functionalrole of p-glycoprotein in limitingintestinalabsorption of drugs: contribution of passive permeability to p-glycoprotein-mediated efflux transport[J]. Mol Pharm, 2005, 2(1): 12-21…