H Lim, SE Kim, YH Lee, YH Hwang, SH Kim, MY Kim… - Virology, 2022 - Elsevier
… the group immunized with the DNAvaccine encoding the full-length S protein presented a reduced … Similar to the MERS-CoVDNAvaccine, the S1 antigen showed higher NAb titers and …
Y Zhou, S Jiang, L Du - Expert review of vaccines, 2018 - Taylor & Francis
… adenovirus vector vaccine (ChAdOx1) and a DNAvaccine (… immunogenicity of MERS-CoV RBD-based subunit vaccines … S candidatevaccines against MERS-CoV infection, careful …
… and other pathogenic human CoVs such as MERS-CoV and SARS-CoV have … based vaccines target the S1 subunit, making S1 an attractive and probably safer immunogen for vaccine …
… To test the immunogenicity of our vaccinecandidates against multiple MERS-CoV strains—… on the surface of transduced cells after DNAimmunization may have contributed to the …
J Choi, J Goo, E Yang, DI Jung, S Lee, S Rho… - Journal of …, 2020 - Am Soc Microbiol
… immunogenicity of MERS-CoV S subunits as a DNAvaccine, human codon-optimized pSΔER, pSΔTM, pS1, pRBD, and pS2 DNA … vaccinecandidates (pSΔER DNA prime-SΔTM protein …
TRF Smith, A Patel, S Ramos, D Elwood, X Zhu… - Nature …, 2020 - nature.com
… immunization of small and large animal models with DNAvaccines encoding MERS-CoV spike (S) protein … In subjects immunized with INO-4700 (MERS-CoV S proteinDNAvaccine) …
A Dey, TMC Rajanathan, H Chandra, HPR Pericherla… - Vaccine, 2021 - Elsevier
… immunization in animal models with DNAvaccines encoding MERS-CoVspike (S) protein … In subjects immunized with MERS-CoVDNAvaccine durable neutralizing antibodies (nAbs) …
IK Yoon, JH Kim - The Lancet Infectious Diseases, 2019 - thelancet.com
… of GLS-5300, the first DNAvaccinecandidate against MERS coronavirus to enter clinical trials. … it remains difficult to interpret the relevance of the immunogenicity parameters that were …
L Du, W Tai, Y Zhou, S Jiang - Expert review of vaccines, 2016 - Taylor & Francis
… An ideal MERS vaccinecandidate should have high immunogenicity and strong potency, as … Since such DNAvaccines encode MERS-CoV full-length S protein, the potential induction …