[PDF][PDF] 重离子束辐射诱导细胞双链断裂(DSBs) 损伤及修复机理的研究进展

任军乐, 郭晓鹏, 雷彩荣, 张苗苗, 柴冉… - Journal of Radiation …, 2023 - researching.cn
… findings on DNA damage characteristics and repair pathways … the selection mechanism of
DSB repair pathways in cells is … of DNA repair pathway choices in ionising radiation-induced

重离子的辐射生物效应及其在生命科学中的应用

贾蓉, 苏锋涛, 胡步荣 - 生物技术通报, 2018 - biotech.aiijournal.com
… helixes of DNA,ie,the clustered DNA damage. The complex damages impede the binding of
… analyze the clustered DNA damage induced by heavy ions and its repairing mechanism,as …

电催化过氧化氢还原的纳米材料作为潜在的辐射防护剂

贾瑞虹, 张瑾轩, 张晓东, 李美仙 - 电化学, 2019 - electrochem.xmu.edu.cn
… within the body, repairing DNA damage, and recovering all vital … surface activities can recover
radiation induced DNA … as tumor chemotherapy, mutagenesis prevention, anti1cell trans1 …

[PDF][PDF] 1~ 20 eV 低能电子对DNA 的多重损伤及其瞬态阴离子机制

庄浦祥, 董艳芳, 邵宇, 郑宜 - 辐射研究与辐射工艺学报, 2021 - fs.sinap.ac.cn
… Delayed repair of radiation induced clustered DNA damage: friend or foe? [J]. Mutation
Research, 2011… Non-DSB clustered DNA lesions. Does theory colocalize with the experiment?[J]. …

[PDF][PDF] 重离子诱变微生物育种的研究进展

汶瑛, 于雪, 吴玉洁, 张威, 陈拓, 刘光琇 - 微生物学杂志, 2021 - wswx.cnjournals.com
… in heavy ion mutagenesis in microbial breeding… DNA 团簇损伤( Clustered DNA damage)
[19]比单个 DNA 损伤修复更困难或无法修复.因此,高LET 的重离子束诱导细胞产生修复困难的DNA

[PDF][PDF] 基于大肠杆菌的重离子辐射靶点序列定位和LacI 突变分析的实验体系构建及验证

金铭, 王婷, 刘斌美, 卞坡 - 原子核物理评论, 2023 - npr.ac.cn
… mainly induces clustered DNA damage, the evolution of which to genetic variation is more …
of DNA double strand breaks(DSB) in the core of heavy ion radiation-induced cluster damage. …

[PDF][PDF] 非同源末端连接修复相关因子对DNA 损伤修复调控及肿瘤治疗作用的研究进展

李蔚蔚, 孔金昕, 漆永梅… - 中国药理学与毒理学杂志, 2015 - cjpt.magtechjournal.com
… cross-complementing 4 / DNA ligase Ⅳ and XRCC4-like factor)in the progress of NHEJ
play very important roles in mediating DNA damage repair(DDR),and the change of any factor …

[HTML][HTML] γ射线照射后小鼠XRCC修复基因的mRNA表达

王芹, 岳井银, 李进, 穆传杰, 樊飞跃 - 中国辐射卫生, 2006 - html.rhhz.net
… X射线修复交叉互补基因(X ray repair cross complementing genes, XRCC)是参与DNA损伤修复
的… Contribution of base lesions to radiation induced clustered DNA damage:implication for …

[PDF][PDF] 基于关联网络的空间辐射防护分子靶标的辨识与预测

谢达菲, 关华, 樊婵, 胡赛, 刘晓丹, 谢漪, 王豫, 张红… - 科学通报, 2020 - researchgate.net
… Interplay of space radiation and microgravity in DNA damage and DNA damage response. …
mechanisms in radiation-induced injury and medical protection against cosmic radiation. …

羟基脲联合辐射对沉默ATRX 后细胞周期及凋亡的影响

田宏远, 尹彩云, 王丽, 胡沛芸, 张晨阳… - 吉林大学学报(医学 …, 2023 - xuebao.jlu.edu.cn
目的: 探讨羟基脲(HU) 联合辐射对沉默α-地中海贫血/精神发育迟滞综合征X 染色体相关蛋白(ATRX)
后A549 细胞周期和凋亡的影响, 并阐明其可能的分子机制. 方法: 建立稳定沉默ATRX 的…