… complex multifactorial traits, the predictive value of the disease … complex multifactorial traits
as close to monogenic as possible… For metabolic phenotypes, we can measure blood glucose …

… genetic loci for complex diseases. Polygenic risk score combining multiple loci together
has been proved to effectively measure genetic risk of complex diseases, which poses …

… ASD are a polygenic set of neurodevelopmental behaviors that … disease and many do
not appropriately address the social and behavior disorders seen in autism. Many monogenic …

… bloodbrain barrier does not allow the passage from the blood… monogenic disorders and
chronic disease associated to deregulation of cholesterol pathaway. Other multifactorial disease …

… diseases are mainly the diseases of the blood vessels, the … While atherosclerosis is a complex
(polygenic) disease, single… Of the many monogenic diseases that elevate plasma levels of …

… Epidemiological distribution characteristics of peripheral blood … people quitting smoking due
to illness and people with low physical … prevention of age-related diseases such as cancers. …

… either monogenic, including neonatal diabetes mellitus (NDM) and maturity-onset diabetes
of the young (MODY), or polygenetic… ability for models to predict disease in a population. The …

Competing interests: The authors declare that they have no competing interests. 摘要: 目的
探究731 种免疫细胞与乳腺癌的因果关系. 方法使用免疫细胞和乳腺癌的全基因组关联数据(…

… the potential to rescue the genetic disorder directly, rather than … Monogenic NDDs relate to
disorders mediated by mutations … Additionally, the genetic basis of NDDs may be polygenetic, …

… is a multifactorial disease with many factors in addition to aging contributing to the disease
… proven causality, in contrast to monogenic diseases where a single mutation is sufficient. …