Schizophrenia is a severe condition characterized by differences in perception, thought,
emotions, and behavior. It is an incapacitating disease, with tremendous human cost: Those …

Abstract Chromosome 22q11. 2 microdeletions impart a high but incomplete risk for
schizophrenia. Possible mechanisms include genome-wide effects of DGCR8 …

Schizophrenia is a debilitating and complex neurodevelopmental disorder. Over the last 2
decades, our understanding of the genetic architecture of schizophrenia has significantly …

The insula and medial prefrontal cortex (mPFC) share functional, histological,
transcriptional, and developmental characteristics, and they serve higher cognitive functions …

Psychiatric disorders are highly inheritable, and most psychiatric disorders exhibit genetic
overlap. Recent studies associated the 3q29 recurrent deletion with schizophrenia (SCZ) …

Abstract Background The chromosome 22q11. 2 deletion is an extremely high risk genetic
factor for various neuropsychiatric disorders; however, the 22q11. 2 deletion-related brain …

Background The 22q11. 2 deletion syndrome (22q11DS) is the most common chromosomal
interstitial-deletion disorder in humans, occurring in approximately 1 in 4000 live births. 20 …

Abstract The 22q11. 2 deletion syndrome (22q11. 2DS) is caused by recurrent hemizygous
deletions of chromosome 22q11. 2. The phenotype of the syndrome is complex and varies …

Background: Genome-wide scans have revealed that Darwinian natural selection affects
human genome during human evolution, helping us to optimize complex human …

Epidemiological and genetic studies suggest that schizophrenia and autism may share
genetic links. Besides common single nucleotide polymorphisms, recent data suggest that …