[PDF][PDF] 尼群 E

M Rufin, US In - scholar.archive.org
Kollagen gilt als das häufigste und wahrscheinlich wichtigste Strukturprotein in Säugetieren.
In Weichgeweben ordnen sich die Proteinmoleküle vorwiegend zu Fibrillen an, wobei sie …

Proteinglykierung als pathophysiologischer Mechanismus bei Diabetes.

A Simm, A Navarrete-Santos… - Zeitschrift für …, 2012 - search.ebscohost.com
English The incidence of diabetes has increased in the recent years. Diabetes is
characterized by increased sugar concentrations in the blood. Due to this dysregulation …

Molekulare Aspekte der Kollagensynthese

J Brinckmann - Aktuelle Urologie, 2001 - thieme-connect.com
Nach Ausbildung von Kollagenfibrillen im Extrazellularraum erfolgt ihre Stabilisierung durch
die Generierung von intraund intermolekularen Quervernetzungen. Dieser Prozess wird …

Protein glycation as a pathological mechanism in diabetes

A Simm, A Navarrete-Santos, B Hofmann… - … für Gerontologie und …, 2012 - Springer
Die Inzidenz für Diabetes ist in den letzten Jahren stark gestiegen. Diabetes ist durch
erhöhte Zuckerkonzentrationen im Blut gekennzeichnet. Infolge dieser Dysregulation …

[PDF][PDF] Advanced glycation end products (AGEs) in diabetes

N Nass, A Simm - Abhandlungen Sächsische Akademie der …, 2009 - researchgate.net
Life style in the industrialized countries has dramatically changed over the last 100 years.
Due to theses changes as well as an increase in hygienic standards and a medical …

Aging mechanisms of proteins

P Gillery, JC Monboisse, FX Maquart… - Diabete & …, 1991 - europepmc.org
All the living molecules appear to suffer from the deleterious effects of aging, but the primary
mechanisms of this inexorable evolution are still unknown. In the case of proteins, two major …

Advanced glycation and aging

A Gugliucci - … Linking Aging, Diseases and Biological Age …, 2017 - api.taylorfrancis.com
Aging may be defined as the time-dependent functional decline that affects most living
organisms. Almost four decades ago, Monnier and Cerami offered a Maillard (the browning …

Analysis of Advanced Glycation End Product (AGE) Content in Tendon Tissue with Fluorometric and Colorimetric Assays

M Rakuš - 2023 - repositum.tuwien.at
Being the most abundant protein in the human body, constituting about~ 25% of all protein
mass, collagen provides the necessary biomechanical characteristics, structural stability …

[HTML][HTML] Age-and diabetes-related nonenzymatic crosslinks in collagen fibrils: candidate amino acids involved in advanced glycation end-products

A Gautieri, A Redaelli, MJ Buehler, S Vesentini - Matrix Biology, 2014 - Elsevier
Ageing and diabetes share a common deleterious phenomenon, the formation of Advanced
Glycation Endproducts (AGEs), which accumulate predominantly in collagen due to its low …

Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes

RG Paul, AJ Bailey - The international journal of biochemistry & cell biology, 1996 - Elsevier
The most serious late complications of ageing and diabetes mellitus follow similar patterns
in the dysfunction of retinal capillaries, renal tissue, and the cardiovascular system. The …