革兰氏阴性菌Ⅴ 型分泌系统是细菌病原蛋白分泌的主要途径之一, 可分为Ⅴa–Ⅴe 5 个亚型,
其中Ⅴa 型(即经典的单体自转运蛋白) 是细菌毒力和黏附因子向细胞外分泌的重要工具 …

蛋白质分泌系统是细菌与外界交流的重要工具. 革兰氏阴性细菌的Ⅵ 型蛋白分泌系统(T6SS)
可以转运分泌蛋白至细菌和真核细胞内, 在菌间竞争中发挥重要作用, 是细菌的一种重要的生存 …

The classical monomeric autotransporters are ubiquitously used by Gram-negative bacteria
to export virulence and colonization factors to their cell surface or into their surroundings …

Background Bacterial surface display technique enables the exogenous proteins or
polypeptides displayed on the bacterial surface, while maintaining their relatively …

Gram-negative bacteria use the type-V secretion pathway to expose proteins at their cell
surface, many of which have virulence functions. Translocation of those proteins across the …

Autotransporters belong to a group of virulence factors secreted by Gram-negative bacteria
using a simple mechanism termed type V or autotransporter secretion. These large proteins …

The two membranes of Gram-negative bacteria contain protein machines that have a
general function in their assembly. To interact with the extra-cellular milieu, Gram-negatives …

Cell surface display of proteins can be used for several biotechnological applications such
as the screening of protein libraries, whole cell biocatalysis and live vaccine development …

The plasmid encoded toxin, Pet, is a prototypical member of the serine protease
autotransporters of the Enterobacteriaceae. In addition to the passenger and β-domains …