orcid: 0000-0002-4694-8513 (Hannah C. Leeson) 0000-0002-8225-3671 (Tailoi Chan-Ling)
0000-0003-2066-3031 (Michael D. Lovelace) 0000-0003-0161-2204 (Jeremy C. Brownlie) …

Neurogenesis is a persistent and essential feature of the adult mammalian hippocampus.
Granular neurons generated from resident pools of stem or progenitor cells provide a …

Identifying the signaling mechanisms that regulate adult neurogenesis is essential to
understanding how the brain may respond to neuro-inflammatory events. P2X7 receptors …

A large body of evidence suggests the involvement of the ATP-gated purinergic receptor
P2X7 (P2X7R) in neurodegenerative diseases, including Alzheimer's disease. While it is …

P2X7 receptors regulate different aspects of neuronal development, including neurogenesis,
dendritic outgrowth, and axonal elongation. Primary neuronal culture is a widely used model …

The expression and function of P2X7 receptors in adult CNS have been widely studied,
however, the roles of these purinergic receptors in human neural development has largely …

Abstract The P2X7 receptor (P2X7R) is a cation membrane channel activated by
extracellular adenosine 5′-triphosphate. Activation of this receptor results in numerous …

Activation of the ATP-gated P2X7 receptor (P2X7R), implicated in numerous diseases of the
brain, can trigger diverse responses such as the release of pro-inflammatory cytokines …

Microglial activation is an integral part of neuroinflammation associated with many
neurodegenerative conditions. Interestingly, a number of neurodegenerative conditions …

Activation of the ATP-gated P2X7 receptor (P2X7R), implicated in numerous diseases of the
brain, can trigger diverse responses such as the release of pro-inflammatory cytokines …