肠道-微生物组-脑轴: 帕金森病中迷走神经, α-突触核蛋白和大脑之间的串扰

JCC dos Santos, LF Oliveira, FM Noleto… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
This critical review of the literature shows that there is a close link between the microbiome,
the gut, and the brain in Parkinson's disease. The vagus nerve, the main component of the …

Gut-microbiome-brain axis: the crosstalk between the vagus nerve, alpha-synuclein and the brain in Parkinson's disease

JCC Dos Santos, LF Oliveira, FM Noleto… - Neural Regeneration …, 2023 - journals.lww.com
This critical review of the literature shows that there is a close link between the microbiome,
the gut, and the brain in Parkinson's disease. The vagus nerve, the main component of the …

[HTML][HTML] Research progress of microbiota-gut-brain axis in parkinson's disease

W Zhang, Y Ye, J Song, T Sang, T Xia, L Xie… - Journal of Integrative …, 2023 - imrpress.com
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by
misfolding of α-synuclein. Clinical manifestations include slowly developing resting tremor …

New hope for Parkinson's disease treatment: Targeting gut microbiota

HX Fan, S Sheng, F Zhang - CNS Neuroscience & Therapeutics, 2022 - Wiley Online Library
There might be more than 10 million confirmed cases of Parkinson's disease (PD) worldwide
by 2040. However, the pathogenesis of PD is still unclear. Host health is closely related to …

Gut Microbes in Parkinson's Disease: Opportunities for Microbial-Based Therapies

A Markidi, JD Elford, C Berkers, AD Kraneveld… - The Gut-Brain Axis, 2024 - Elsevier
Parkinson's disease is characterized by motor impairments due to the progressive
degeneration of dopaminergic neurons in the substantia nigra of the midbrain, but …

From the Gut to the Brain: Is Microbiota a New Paradigm in Parkinson's Disease Treatment?

C Vilela, B Araújo, C Soares-Guedes, R Caridade-Silva… - Cells, 2024 - mdpi.com
Parkinson's disease (PD) is recognized as the second most prevalent primary chronic
neurodegenerative disorder of the central nervous system. Clinically, PD is characterized as …

[HTML][HTML] Multidirectional associations between the gut microbiota and Parkinson's disease, updated information from the perspectives of humoral pathway, cellular …

X Jia, Q Chen, Y Zhang, T Asakawa - Frontiers in Cellular and …, 2023 - ncbi.nlm.nih.gov
The human gastrointestinal tract is inhabited by a diverse range of microorganisms,
collectively known as the gut microbiota, which form a vast and complex ecosystem. It has …

Brain-gut-microbiota axis in Parkinson's disease: A historical review and future perspective

S Dong, M Sun, C He, H Cheng - Brain Research Bulletin, 2022 - Elsevier
Parkinson's disease (PD) is the second most common degenerative disease of the central
nervous system (CNS) after Alzheimer's disease. In addition to the typical motor symptoms …

The role of an altered gut microbiome in Parkinson's disease: a narrative review

S Hashish, M Salama - Applied Microbiology, 2023 - mdpi.com
Parkinson's disease is a debilitating multisystemic disorder affecting both the central and
peripheral nervous systems. Accumulating evidence suggests a potential interaction …

Parkinson's disease: Are gut microbes involved?

AO Omotosho, YA Tajudeen, HJ Oladipo… - Brain and …, 2023 - Wiley Online Library
Introduction Parkinson's disease (PD) is a neurodegenerative disorder that affects more than
10 million individuals worldwide. It is characterized by motor and sensory deficits. Research …