The study of Genetic Epidemiology has historically focused on the inheritance of genetic factors and phenotypes within families. In fact, much of genetics involves the study of …
MJ Khoury, S Bowen, D Dotson, M Gwinn - Centers for Disease Control and …, 2020 - cdc.gov
Genetic epidemiology is a relatively new discipline that seeks to elucidate the role of genetic factors and their interaction with environmental factors in the occurrence of disease in …
K Higasa, N Miyake, J Yoshimura, K Okamura… - Journal of human …, 2016 - nature.com
Whole-genome and-exome resequencing using next-generation sequencers is a powerful approach for identifying genomic variations that are associated with diseases. However …
JD Terwilliger, HHH Göring - Human biology, 2009 - BioOne
In the 20th century geneticists began to unravel some of the simpler aspects of the etiology of inherited diseases in humans. The theory of linkage analysis was developed and applied …
GR Kazeem, M Farrall - Annals of human genetics, 2005 - Wiley Online Library
Genetic‐association studies are widely expected to unravel the genetic basis of complex diseases. The population‐based case‐control study, a commonly used approach for …
K Hirayama, Y Baba, H Arata - 1979 - u-ryukyu.repo.nii.ac.jp
The Nansei Islands belong to two prefectures, Kagoshima and Okinawa, and consist of jnany isolated islands. From the viewpoint of human genetics, they can be divided into two …
A Koizumi - Nihon Eiseigaku zasshi. Japanese Journal of Hygiene, 2010 - europepmc.org
Genetic dissection of diseases is one of the epoch-making achievements in modern medicine. Positional cloning is a key method to isolate disease-related genes. For positional …