To date, most genome-wide association studies (GWAS) and studies of fine-scale
population structure have been conducted primarily on Europeans. Han Chinese, the largest …

To date, most genome-wide association studies (GWAS) and studies of fine-scale
population structure have been conducted primarily on Europeans. Han Chinese, the largest …

Population stratification acts as a confounding factor in genetic association studies and may
lead to false-positive or false-negative results. Previous studies have analyzed the genetic …

Low lean body mass (LBM) is related to a series of health problems, such as osteoporotic
fracture and sarcopenia. Here we report a genomewide association (GWA) study on LBM …

Population stratification is a potential problem for genome-wide association studies (GWAS),
confounding results and causing spurious associations. Hence, understanding how allele …

Because population stratification can cause spurious associations in case-control studies,
understanding the population structure is important. Here, we examined Japanese …

Large-scale multi-ethnic cohorts offer unprecedented opportunities to elucidate the genetic
factors influencing complex traits related to health and disease among minority populations …

In lieu of large samples of cases and/or controls with hundreds of markers spreading
throughout the human genome, researchers started to notice the dramatic increase of …

It is well-known that population substructure may lead to confounding in case–control
association studies. Here, we examined genetic structure in a large racially and ethnically …

The genome-wide association study (GWAS) has become an effective approach to identify
genetic variants associated with complex traits and diseases. However, population structure …