ε-维尼非林对鱼藤酮诱导帕金森病细胞模型的神经保护: Sirt3 介导Foxo3 去乙酰化的意义

S Zhang, Y Ma, J Feng - 中国神经再生研究(英文版), 2020 - sjzsyj.com.cn
既往研究显示, ε-维尼非林具有抗氧化和抗炎作用, 且可通过激活Sirt3/LKB1/AMPK
信号通路对亨廷顿病具有神经保护作用, 但其是否也对帕金森病发挥作用尚不可知. 实验以3.0 …

Neuroprotective mechanisms of ε-viniferin in a rotenone-induced cell model of Parkinson's disease: significance of SIRT3-mediated FOXO3 deacetylation

S Zhang, Y Ma, J Feng - Neural Regeneration Research, 2020 - journals.lww.com
Abstract Trans-(-)-ε-viniferin (ε-viniferin) has antioxidative and anti-inflammatory effects. It
also has neuroprotective effects in Huntington's disease by activating the SIRT3/LKB1/AMPK …

尼古丁对鱼藤酮诱导帕金森病小鼠模型的神经保护作用机制

张歆悦, 祝柳慧, 何雨, 管莹, 朱洲海, 任惠, 杨兴隆 - 中国组织工程研究, 2024 - cjter.com
尼古丁对鱼藤酮诱导帕金森病小鼠模型的神经保护作用机制 Page 1 5612|中国组织工程研究|第
28卷|第35期|2024年12月 中国组织工程研究 Chinese Journal of Tissue Engineering Research …

SIRT1 is involved in the neuroprotection of pterostilbene against amyloid β 25–35-induced cognitive deficits in mice

L Zhu, F Lu, X Zhang, S Liu, P Mu - Frontiers in pharmacology, 2022 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
amyloid-β (Aβ) deposits and neurofibrillary tangles. Pterostilbene (PTE), a bioactive …

[HTML][HTML] Epothilone B inactivation of Sirtuin1 promotes mitochondrial reactive oxygen species to induce dysfunction and ferroptosis of Schwann cells

Z Liang, N Zhang, X Wang, J Zhang, K Li… - European Journal of …, 2023 - Elsevier
Epothilone B (EpoB) is an FDA-approved anti-neoplastic agent used to treat metastatic
breast cancer; However, its usage is limited due to its severe peripheral neurotoxicity …

SIRT3 acts as a neuroprotective agent in rotenone-induced Parkinson cell model

JY Zhang, YN Deng, M Zhang, H Su, QM Qu - Neurochemical research, 2016 - Springer
SIRT3 is a member of Sirtuins family, which belongs to NAD+ dependent class III histone
deacetylases. Emerging evidence suggests that SIRT3 plays a pivotal role in regulating …

SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of vidarabine against rotenone-induced neural cell injury

L Li, Y Zhang, Z Chen, R Yao, Z Xu, C Xu, F He, H Pei… - Heliyon, 2023 - cell.com
Parkinson's disease (PD) is the second most common neurodegenerative disease in the
world, which is distinguished by the loss of dopaminergic (DA) neurons in the substantia …

雷帕霉素对帕金森病的神经保护: 通过激活自噬通路抑制铁死亡

T Liu, P Wang, H Yin, X Wang, J Lv, J Yuan… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
自噬诱导剂雷帕霉素对帕金森病有神经保护作用, 但作用机制尚不明确. 铁死亡是一种非典型的
细胞死亡方式, 其在帕金森病的病理机制中起着重要作用. 为探讨帕金森病中雷帕霉素与铁死亡 …

[引用][C] 京尼平苷对鱼藤酮诱导的原代神经细胞损伤的保护作用

赵娟 - 2014 - 山西医科大学

[引用][C] 鱼藤酮诱导多巴胺能神经细胞损伤的机制研究

王悦 - 2007 - 北京: 中国协和医科大学研究生院