H Chang, X Cai, HJ Li, WP Liu, LJ Zhao, CY Zhang… - Biological …, 2021 - Elsevier
Background Genome-wide association studies (GWASs) have reported hundreds of genomic loci associated with schizophrenia, yet identifying the functional risk variations is a …
M Li, DR Weinberger - National Science Review, 2017 - academic.oup.com
Recent large-scale genome-wide association studies (GWAS) have enabled the discovery of common genetic variations contributing to risk architectures of schizophrenia in human …
Schizophrenia is a common disorder with a high heritability, but its genetic architecture is still elusive. We implemented whole-genome sequencing (WGS) analysis of 8 families with …
Y Wu, XL Yu, X Xiao, M Li, Y Li - Molecular Neurobiology, 2022 - Springer
Genome-wide association studies (GWAS) have identified a large number of schizophrenia risk variants, and most of them are mapped to noncoding regions. By leveraging multiple …
J Liu, S Li, X Li, W Li, Y Yang, S Guo, L Lv, X Xiao… - BMC medicine, 2021 - Springer
Background Over 200 schizophrenia risk loci have been identified by genome-wide association studies (GWASs). However, the majority of risk loci were identified in …
JC McAfee, S Lee, J Lee, JL Bell, O Krupa, J Davis… - Cell Genomics, 2023 - cell.com
Genome-wide association studies (GWASs) have successfully identified 145 genomic regions that contribute to schizophrenia risk, but linkage disequilibrium makes it challenging …
Y Shi, Z Li, Q Xu, T Wang, T Li, J Shen, F Zhang… - Nature …, 2011 - nature.com
Schizophrenia is a severe mental disorder affecting∼ 1% of the world population, with heritability of up to 80%. To identify new common genetic risk factors, we performed a …
H Yu, H Yan, J Li, Z Li, X Zhang, Y Ma, L Mei… - Molecular …, 2017 - nature.com
Many schizophrenia susceptibility loci have been identified through genome-wide association studies (GWASs) in European populations. However, until recently …
Genome-wide association studies have identified multiple risk variants and loci that show robust association with schizophrenia. Nevertheless, it remains unclear how these variants …