[HTML][HTML] Identification of a functional 339 bp Alu insertion polymorphism in the schizophrenia-associated locus at 10q24. 32

ZH Yang, X Cai, N Qu, LJ Zhao, BL Zhong… - Zoological …, 2020 - ncbi.nlm.nih.gov
Genome-wide association studies (GWAS) have identified multiple single nucleotide
polymorphisms (SNPs) or small indels robustly associated with schizophrenia; however, the …

Functional genomics identify a regulatory risk variation rs4420550 in the 16p11. 2 schizophrenia-associated locus

H Chang, X Cai, HJ Li, WP Liu, LJ Zhao, CY Zhang… - Biological …, 2021 - Elsevier
Background Genome-wide association studies (GWASs) have reported hundreds of
genomic loci associated with schizophrenia, yet identifying the functional risk variations is a …

Illuminating the dark road from schizophrenia genetic associations to disease mechanisms

M Li, DR Weinberger - National Science Review, 2017 - academic.oup.com
Recent large-scale genome-wide association studies (GWAS) have enabled the discovery
of common genetic variations contributing to risk architectures of schizophrenia in human …

Whole-genome sequencing of monozygotic twins discordant for schizophrenia indicates multiple genetic risk factors for schizophrenia

J Tang, Y Fan, H Li, Q Xiang, DF Zhang, Z Li… - Journal of genetics and …, 2017 - Elsevier
Schizophrenia is a common disorder with a high heritability, but its genetic architecture is
still elusive. We implemented whole-genome sequencing (WGS) analysis of 8 families with …

Joint-tissue integrative analysis identified hundreds of schizophrenia risk genes

Y Wu, XL Yu, X Xiao, M Li, Y Li - Molecular Neurobiology, 2022 - Springer
Genome-wide association studies (GWAS) have identified a large number of schizophrenia
risk variants, and most of them are mapped to noncoding regions. By leveraging multiple …

Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia

J Liu, S Li, X Li, W Li, Y Yang, S Guo, L Lv, X Xiao… - BMC medicine, 2021 - Springer
Background Over 200 schizophrenia risk loci have been identified by genome-wide
association studies (GWASs). However, the majority of risk loci were identified in …

[PDF][PDF] Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants

JC McAfee, S Lee, J Lee, JL Bell, O Krupa, J Davis… - Cell Genomics, 2023 - cell.com
Genome-wide association studies (GWASs) have successfully identified 145 genomic
regions that contribute to schizophrenia risk, but linkage disequilibrium makes it challenging …

Common variants on 8p12 and 1q24. 2 confer risk of schizophrenia

Y Shi, Z Li, Q Xu, T Wang, T Li, J Shen, F Zhang… - Nature …, 2011 - nature.com
Schizophrenia is a severe mental disorder affecting∼ 1% of the world population, with
heritability of up to 80%. To identify new common genetic risk factors, we performed a …

Common variants on 2p16. 1, 6p22. 1 and 10q24. 32 are associated with schizophrenia in Han Chinese population

H Yu, H Yan, J Li, Z Li, X Zhang, Y Ma, L Mei… - Molecular …, 2017 - nature.com
Many schizophrenia susceptibility loci have been identified through genome-wide
association studies (GWASs) in European populations. However, until recently …

Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection …

XJ Luo, M Mattheisen, M Li, L Huang… - Schizophrenia …, 2015 - academic.oup.com
Genome-wide association studies have identified multiple risk variants and loci that show
robust association with schizophrenia. Nevertheless, it remains unclear how these variants …