S Wang, Y Peng, R Wang, S Jiao, M Wang… - Nature …, 2020 - nature.com
… needs for COVID-19 therapy as no SARS-CoV-2-specific drugs … and therapeuticefficacy of MW05/LALA on SARS-CoV-2 in … -based therapies for prophylactic and therapeutic treatment …
A Schäfer, DR Martinez, JJ Won, FR Moreira, AJ Brown… - BioRxiv, 2021 - ncbi.nlm.nih.gov
… Here, we demonstrate the in vitro antiviral activity and in vivo therapeuticefficacy of GS-… antiviral activity in mice infected with SARS-CoV-2. Therapeutic GS-621763 significantly reduced …
R Uraki, M Kiso, M Imai, S Yamayoshi, M Ito… - Nature …, 2022 - nature.com
… of US Food and Drug Administration (FDA)-approved therapeutic mAbs against BA.1 … SARS-CoV-2 research 7,8,9 . In addition, using this model, we evaluated the therapeuticefficacy of …
Z Zhang, E Zeng, L Zhang, W Wang, Y Jin, J Sun… - Cell Discovery, 2021 - nature.com
… of antiviral therapies as we previously described 5 . Here we adopted this animal model for evaluation of hACE2-Fc prophylactic and therapeuticefficacy against SARS-CoV-2 infection …
J Santos, S Brierley, MJ Gandhi, MA Cohen… - Viruses, 2020 - mdpi.com
… It also showed therapeuticefficacy against SARS-CoV in a … that therapies with evidence for benefit in SARS-CoV and MERS-CoV infections are more likely to benefit patients with SARS-…
… be targeted by therapeutic agents for treatment of SARS-CoV-2 … treatment, while oxygen therapy is employed for intervention in … drugs/therapeutic agents and treatment for SARS-CoV-2 …
… recommended therapeutic agents, … therapeutic activity. The results of recent studies report that hydroxychloroquine and convalescent plasma demonstrate no efficacy against SARS-CoV…
K Kautsch, J Wiśniowska… - European Journal of …, 2024 - Springer
… ) and Middle East respiratory syndrome coronavirus (MERS-CoV) was … therapeuticefficacy, but its safety profile allowed the initiation of drug repurposing research, including SARS-CoV-…
… we assessed the in vivo therapeutic activity of another neutralizing anti-SARS-CoV-2 monoclonal antibody … 8), demonstrate improved therapeuticefficacy compared with wild-type IgG1. …