Effect of dapagliflozin on outpatient worsening of patients with heart failure and reduced ejection fraction: a prespecified analysis of DAPA-HF

KF Docherty, PS Jhund, I Anand, O Bengtsson… - Circulation, 2020 - Am Heart Assoc
… in Heart Failure), dapagliflozin, added to guideline-recommended therapies, reduced the
risk of mortality and heart failure (… , and the effects of dapagliflozin on these additional events. …

The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

ME Nassif, SL Windsor, BA Borlaug, DW Kitzman… - Nature medicine, 2021 - nature.com
… a–d, Effects of dapagliflozin on the primary endpoint and its components. Effects of dapagliflozin
versus placebo at 12 weeks on KCCQ-CS (a), KCCQ-TS (b), KCCQ-physical limitations …

Effects of dapagliflozin according to the heart failure collaboratory medical therapy score: insights from DAPA-HF

JH Butt, P Dewan, EM DeFilippis, T Biering-Sørensen… - Heart Failure, 2022 - jacc.org
… Therefore, in the present report, we examined the effects of dapagliflozin according to an …
Collectively, these findings suggest that the substantial effects of dapagliflozin are incremental, …

[HTML][HTML] Effect of Dapagliflozin in Patients with Heart Failure: A Systematic Review and Meta-Analysis

AE Ali, MS Mazroua, M ElSaban, N Najam… - Global Heart, 2023 - ncbi.nlm.nih.gov
… randomized controlled trials investigating the effects of dapagliflozin in heart failure patients.
… This meta-analysis only included clinical trials studying the effects of dapagliflozin and …

Effect of dapagliflozin on anaemia in DAPA‐HF

KF Docherty, JP Curtain, IS Anand… - … of heart failure, 2021 - Wiley Online Library
heart failure event, defined as a worsening heart failure event (hospitalization or an urgent
visit resulting in intravenous therapy for heart failure) or … The effects of dapagliflozin, compared …

Effect of dapagliflozin on health status in patients with preserved or mildly reduced ejection fraction

MN Kosiborod, AS Bhatt, BL Claggett… - Journal of the American …, 2023 - jacc.org
Heart failure (HF) with mildly reduced and preserved ejection … Our findings confirm these
beneficial effects of dapagliflozin … to assess the effects of dapagliflozin on clinical outcomes …

Acute pleiotropic effects of dapagliflozin in type 2 diabetic patients with heart failure with reduced ejection fraction: a crossover trial

F Ilyas, L Jones, SL Tee, M Horsfall, A Swan… - … heart failure, 2021 - Wiley Online Library
… the rapid effects of dapagliflozin in heart failure with reduced … morbidity and mortality benefits
in heart failure (HF) with reduced … energetics and arrhythmic effects of dapagliflozin in type 2 …

Impact of dapagliflozin on left ventricular diastolic function of patients with type 2 diabetic mellitus with chronic heart failure

F Soga, H Tanaka, K Tatsumi, Y Mochizuki… - Cardiovascular …, 2018 - Springer
… Type 2 diabetes mellitus (T2DM) is a major cause of heart failure (HF), both with reduced
ejection … Findings of a large clinical trial to evaluate the effects of dapagliflozin, another SGLT2 …

Metabolomic profiling of the effects of dapagliflozin in heart failure with reduced ejection fraction: DEFINE-HF

S Selvaraj, Z Fu, P Jones, LC Kwee, SL Windsor… - Circulation, 2022 - Am Heart Assoc
Background: Sodium-glucose cotransporter-2 inhibitors are foundational therapy in patients
with heart failure with reduced ejection fraction (HFrEF), but underlying mechanisms of …

Dapagliflozin for heart failure: is it a class effect?

GM Raj, M Wyawahare - Future cardiology, 2020 - Future Medicine
… in patients with heart failure with preserved … heart failure with preserved ejection fraction)
[12] trials are awaited to ascertain the possible beneficial effects of empagliflozin in heart failure