Efficacy and safety of dapagliflozin according to aetiology in heart failure with reduced ejection fraction: insights from the DAPA‐HF trial

JH Butt, JC Nicolau, S Verma… - … of heart failure, 2021 - Wiley Online Library
… To compare the effects of dapagliflozin vs. placebo on the primary outcome and secondary
clinical outcomes in patients with ischaemic and non-ischaemic aetiology, respectively, time-…

The clinical outcomes of dapagliflozin in patients with acute heart failure: A randomized controlled trial (DAPA-RESPONSE-AHF)

AN Emara, M Wadie, NO Mansour… - European Journal of …, 2023 - Elsevier
… The effects of dapagliflozin on different natriuretic and diuretic responses are presented
in Table 3. Spot urinary Na concentration 2 h after randomization was modestly higher in the …

Effects of dapagliflozin in heart failure with preserved ejection fraction and chronic obstructive pulmonary disease: an analysis of the DELIVER trial

J Butt, H Lu, T Kondo, E Bachus… - European Heart …, 2023 - academic.oup.com
Introduction Chronic obstructive pulmonary disease (COPD) is a common comorbidity in heart
failure (HF) with preserved ejection fraction (HFpEF) and associated with worse outcomes…

Prediction of the effect of dapagliflozin on kidney and heart failure outcomes based on short-term changes in multiple risk markers

NMA Idzerda, BV Stefansson, MJ Pena… - Nephrology Dialysis …, 2020 - academic.oup.com
… glycaemic effects of dapagliflozin only modestly contribute in reducing the risk of kidney
outcomes. Non-glycaemic effects of dapagliflozin… suggested beneficial effects of dapagliflozin on …

Effects of dapagliflozin on congestion assessed by remote pulmonary artery pressure monitoring

W Mullens, P Martens, O Forouzan, J Dauw… - … Heart Failure, 2020 - Wiley Online Library
… Single-centre open label observational pilot trial, to investigate the short-term effects of
dapagliflozin in consecutive heart failure and reduced ejection fraction patients with elevated …

Economic evaluation of dapagliflozin in the treatment of patients with heart failure: a systematic review

M Wu, S Qin, L Wang, C Tan, Y Peng, X Zeng… - Frontiers in …, 2022 - frontiersin.org
… The Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure (DAPA-HF) trial
has demonstrated the effects of dapagliflozin in patients with HFrEF by reducing HF …

Efficacy and safety of dapagliflozin in heart failure with mildly reduced or preserved ejection fraction according to age: the DELIVER trial

A Peikert, FA Martinez, M Vaduganathan… - … : Heart Failure, 2022 - Am Heart Assoc
heart failure events (defined as either unplanned hospitalization or urgent heart failure visit
… included the total number of heart failure events (hospitalization for heart failure, urgent …

Relationship of dapagliflozin with serum sodium: findings from the DAPA-HF trial

SE Yeoh, KF Docherty, PS Jhund, MC Petrie… - Heart Failure, 2022 - jacc.org
… the prognostic importance of hyponatremia and the effects of dapagliflozin on serum sodium
in the DAPA-HF (Dapagliflozin And Prevention of Adverse outcomes in Heart Failure) trial. …

Influence of NT-proBNP on efficacy of dapagliflozin in heart failure with mildly reduced or preserved ejection fraction

PL Myhre, M Vaduganathan, BL Claggett, ZM Miao… - Heart Failure, 2022 - jacc.org
… This analysis, which evaluates the treatment effects of dapagliflozin according to baseline
NT-proBNP levels in patients with HFmrEF or HFpEF. This is particularly relevant, as elevated …

Serial assessment of high-sensitivity cardiac troponin and the effect of dapagliflozin in patients with heart failure with reduced ejection fraction: an analysis of the …

DD Berg, KF Docherty, N Sattar, P Jarolim, P Welsh… - Circulation, 2022 - Am Heart Assoc
… risk of worsening heart failure and death in patients with heart failure with reduced ejection
… of changes in hsTnT over time, the effects of dapagliflozin on clinical outcomes in relation to …