Dapagliflozin improves heart failure symptoms and physical limitations across the full range of ejection fraction: pooled patient-level analysis from DEFINE-HF and …

ME Nassif, SL Windsor, K Gosch… - … : Heart Failure, 2023 - Am Heart Assoc
effects of dapagliflozin versus placebo on KCCQ-CSS at 12 weeks specifically in patients with
EF of ≥65%. The effects of dapagliflozin … test whether these effects of dapagliflozin versus …

Dapagliflozin and recurrent heart failure hospitalizations in heart failure with reduced ejection fraction: an analysis of DAPA-HF

PS Jhund, P Ponikowski, KF Docherty, SB Gasparyan… - Circulation, 2021 - Am Heart Assoc
… but has not routinely been applied in heart failure. In part, this … of Adverse-Outcomes in Heart
Failure), the sodium-glucose … worsening heart failure (HF) in patients with heart failure and …

Cost-effectiveness of dapagliflozin for treatment of patients with heart failure with reduced ejection fraction

JT Parizo, JD Goldhaber-Fiebert, JA Salomon… - JAMA …, 2021 - jamanetwork.com
… Although a post hoc analysis indicated the effects of dapagliflozin were independent of
sacubitril-valsartan use, further evaluation of the interaction between dapagliflozin and sacubitril-…

Effect of dapagliflozin on clinical outcomes in patients with chronic kidney disease, with and without cardiovascular disease

JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Circulation, 2021 - Am Heart Assoc
… death), the composite of hospitalization for heart failure or cardiovascular death, and all-cause …
Here, we report the effects of dapagliflozin on the prespecified kidney and cardiovascular …

The effect of dapagliflozin on ventricular arrhythmias, cardiac arrest, or sudden death in people with heart failure: a tick in another box for sodium-glucose …

T Koufakis, G Giannakoulas, P Zebekakis… - Expert Opinion on …, 2022 - Taylor & Francis
… In this paper, we discuss recently published findings on the effects of dapagliflozin on the
incidence of VA, cardiac arrest, and sudden death, explaining how these could influence …

[HTML][HTML] Effect of dapagliflozin on exercise capacity and cardiovascular risk in patients with heart failure

R Nazer, M Albratty, MI Aldhahi, M Alqurashy… - Healthcare, 2022 - mdpi.com
… A recent RCT looked at the effects of dapagliflozin on exercise capacity in 90 stable patients
… Outcomes in Heart Failure (DAPA-HF) trial to examine the effects of dapagliflozin on …

Efficacy of dapagliflozin in black versus white patients with heart failure and reduced ejection fraction

KF Docherty, MO Ogunniyi, IS Anand, AS Desai… - Heart Failure, 2022 - jacc.org
… The effects of dapagliflozin on eGFR, body weight, SBP, and hematocrit were directionally
similar in Black and White patients. In this respect, it is worth noting that the blood pressure …

Dapagliflozin and atrial fibrillation in heart failure with reduced ejection fraction: insights from DAPA‐HF

JH Butt, KF Docherty, PS Jhund… - … of heart failure, 2022 - Wiley Online Library
… Dapagliflozin reduced the risk of worsening heart failure events and death, and improved …
(A) Effects of dapagliflozin compared with placebo on clinical outcomes according AF status …

Effect of Dapagliflozin on 6-Minute Walk Distance in Heart Failure With Preserved Ejection Fraction: PRESERVED-HF

GD Lewis, K Gosch, LP Cohen, ME Nassif… - … : Heart Failure, 2023 - Am Heart Assoc
… The present study has multiple strengths, most notably its focus on the effects of dapagliflozin
on 6MWT distance in an appropriately powered randomized clinical trial, the inclusion of …

Nature and magnitude of the benefits of dapagliflozin and empagliflozin for heart failure

JGF Cleland - Circulation, 2024 - Am Heart Assoc
… With Heart Failure) trial comprised 2 randomized, placebo-controlled trials of heart failure—…
with HFpEF—which investigated the effects of dapagliflozin on KCCQ Total Symptom Score …