(+)-Thalianatriene and (−)-Retigeranin B Catalyzed by Sesterterpene Synthases from Arabidopsis thaliana
J Shao, QW Chen, HJ Lv, J He, ZF Liu, YN Lu… - Organic …, 2017 - ACS Publications
Two GFPPS linked (+)-thalianatriene (1) and (−)-retigeranin B (2) sesterterpene synthase
genes were identified from the genome of Arabidopsis thaliana. 1 possesses an
unprecedented 11–6–5 tricyclic ring system, while 2 contains a characteristic 5–5–5–6–5
pentacyclic ring system. Their structures were determined by extensive NMR spectroscopy,
chemical derivatization, and X-ray crystallography. The variable-temp NMR measurement of
3, a diepoxy-bearing derivative of 1, enables us to completely assign the NMR signals of the …
genes were identified from the genome of Arabidopsis thaliana. 1 possesses an
unprecedented 11–6–5 tricyclic ring system, while 2 contains a characteristic 5–5–5–6–5
pentacyclic ring system. Their structures were determined by extensive NMR spectroscopy,
chemical derivatization, and X-ray crystallography. The variable-temp NMR measurement of
3, a diepoxy-bearing derivative of 1, enables us to completely assign the NMR signals of the …
[引用][C] (+)-Thalianatriene and (−)-Retigeranin B Catalyzed by Sesterterpene Synthases from Arabidopsis thaliana
S Jie, C Qing-Wen, L Hua-Jun, H Juan, L Zhi-Feng… - 2017