(6)-Gingerolinduced myeloid leukemia cell death is initiated by reactive oxygen species and activation of miR-27b expression
Abstract The natural polyphenolic alkanone (6)-gingerol (6G) has established anti-
inflammatory and antitumoral properties. However, its precise mechanism of action in
myeloid leukemia cells is unclear. In this study, we investigated the effects of 6G on myeloid
leukemia cells in vitro and in vivo. The results of this study showed that 6G inhibited
proliferation of myeloid leukemia cell lines and primary myeloid leukemia cells while sparing
the normal peripheral blood mononuclear cells, in a concentration-and time-dependent …
inflammatory and antitumoral properties. However, its precise mechanism of action in
myeloid leukemia cells is unclear. In this study, we investigated the effects of 6G on myeloid
leukemia cells in vitro and in vivo. The results of this study showed that 6G inhibited
proliferation of myeloid leukemia cell lines and primary myeloid leukemia cells while sparing
the normal peripheral blood mononuclear cells, in a concentration-and time-dependent …
(6)-Gingerolinduced myeloid leukemia cell death is initiated by reactive oxygen species and activation of miR-27b expression.
NR Namrata Rastogi, RK Gara, RT Rachana Trivedi… - 2014 - cabidigitallibrary.org
Abstract The natural polyphenolic alkanone (6)-gingerol (6 G) has established anti-
inflammatory and antitumoral properties. However, its precise mechanism of action in
myeloid leukemia cells is unclear. In this study, we investigated the effects of 6 G on myeloid
leukemia cells in vitro and in vivo. The results of this study showed that 6 G inhibited
proliferation of myeloid leukemia cell lines and primary myeloid leukemia cells while sparing
the normal peripheral blood mononuclear cells, in a concentration-and time-dependent …
inflammatory and antitumoral properties. However, its precise mechanism of action in
myeloid leukemia cells is unclear. In this study, we investigated the effects of 6 G on myeloid
leukemia cells in vitro and in vivo. The results of this study showed that 6 G inhibited
proliferation of myeloid leukemia cell lines and primary myeloid leukemia cells while sparing
the normal peripheral blood mononuclear cells, in a concentration-and time-dependent …
以上显示的是最相近的搜索结果。 查看全部搜索结果