In our work we focus on the principles of organizing the interaction of law enforcement agencies in the fight against financial crime. It is the special principles of engagement that emphasize. One of the main special principles is the principle of objectivity. Its main task is to combine the efforts of several law enforcement agencies (or their units), provided that there are real facts to begin such mutual work. The principle of differentiation of competence, systematicity, plannedness, efficiency, as well as one of the equally important principles–the principle of responsibility, are also considered. Unfortunately, at this stage, the organization of combating financial crime cannot be considered satisfactory. One of the main reasons is the lack of properly organized, at the managerial, organizational and tactical levels between the operational units of law enforcement agencies in detecting, documenting and disclosing crimes in the economic sphere. It is known that the main tools of the science of the legal cycle are terms and concepts. Therefore, the purpose of our study requires first of all to clarify the essence and content of the principles of organizing law enforcement cooperation in the fight against economic crime, namely the specific principles.