Neurogenesis in the adult hippocampus can be up-or downregulated in response to a
variety of physiological and pathological conditions. Among these, dysregulation of
hippocampal neurogenesis has been recently implicated in the pathogenesis of depression.
In addition, in animal models of depression, a variety of antidepressant treatments reverse
that condition by increasing neurogenesis. As one night sleep deprivation is known to
improve mood in depressed patients for at least 1 day, we investigated whether a …