[HTML][HTML] The human transcription factors

SA Lambert, A Jolma, LF Campitelli, PK Das, Y Yin… - Cell, 2018 - cell.com
… Historically, the term transcription factor has been applied to describe any protein involved
in transcription and/or capable of altering gene-expression levels. In the current vernacular, …

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework

A Khan, O Fornes, A Stigliani, M Gheorghe… - Nucleic acids …, 2018 - academic.oup.com
… The JASPAR 2018 CORE vertebrate collection of PFMs was used to predict TF-binding sites
in the human … using a RESTful API and through the JASPAR 2018 R/Bioconductor package. …

Benchmark and integration of resources for the estimation of human transcription factor activities

L Garcia-Alonso, CH Holland, MM Ibrahim… - Genome …, 2019 - genome.cshlp.org
… , transcription factors (TFs) are key proteins in linking signaling transduction networks to
gene-specific transcriptional … JASPAR 2018: update of the open-access database of transcription

Transcription factor profiling reveals molecular choreography and key regulators of human retrotransposon expression

X Sun, X Wang, Z Tang, M Grivainis… - Proceedings of the …, 2018 - National Acad Sciences
transcriptional regulators using ENCODE ChIP-seq datasets. We revealed the binding of …
transcription factors, including Myc and CTCF, to the 5′ UTR promoter of the youngest human

Profiling of human molecular pathways affected by retrotransposons at the level of regulation by transcription factor proteins

D Nikitin, D Penzar, A Garazha, M Sorokin… - Frontiers in …, 2018 - frontiersin.org
factors of evolution of gene expression regulatory networks. For example, ~30% of all
transcriptional factor p53 binding sites in the human … TFBS within the human-specific endogenous …

TFClass: expanding the classification of human transcription factors to their mammalian orthologs

E Wingender, T Schoeps, M Haubrock… - Nucleic acids …, 2018 - academic.oup.com
TFClass is a resource that classifies eukaryotic transcription factors (TFs) according to their
DNA-binding domains (DBDs), available online at http://tfclass.bioinf.med.uni-goettingen.de . …

Global reference mapping of human transcription factor footprints

J Vierstra, J Lazar, R Sandstrom, J Halow, K Lee… - Nature, 2020 - nature.com
… rather than by differential transcription factor occupancy within … variants that affect transcription
factor occupancy are nearly … density of human genetic variation within transcription factor

Human transcription factor protein interaction networks

H Göös, M Kinnunen, K Salokas, Z Tan, X Liu… - Nature …, 2022 - nature.com
… Although our study represents currently the most comprehensive interactome analysis of
the human transcription factors, we acknowledge some limitations of this current study. These …

Characterization of human dosage-sensitive transcription factor genes

Z Ni, XY Zhou, S Aslam, DK Niu - Frontiers in genetics, 2019 - frontiersin.org
… The dosage sensitivity of transcription factor (TF) genes is particularly interesting because
their products are essential in regulating the expression of genetic information. From four …

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

A Mathelier, O Fornes, DJ Arenillas, C Chen… - Nucleic acids …, 2016 - academic.oup.com
… -redundant transcription factor (TF) binding profiles representing transcription factor binding
… In addition, we introduced 130 transcription factor flexible models trained on ChIP-seq data …