2-Thioxothiazolidin-4-one compounds and compositions as antimicrobial and antimalarial agents targeting enoyl-ACP reductase of type II fatty acid synthesis pathway …
A Surolia, N Surolia, G Kumar, M Chhibber… - US Patent App. 11 …, 2008 - Google Patents
The current invention presents enoyl-ACP reductase, an enzyme of the type II fatty acid
synthesis pathway as a target for treating human malarias and other infectious diseases. We
also present in the current invention, 2-thioxothiazolidin-4-ones as antimicrobial and
antimalarial agents. We provide 2-thioxothiazolidin-4-ones as antimicrobial and antimalarial
agents either alone or in combination with other known antimicrobial and antimalarial
agents with or without added adjuvants or diluents or carriers.
synthesis pathway as a target for treating human malarias and other infectious diseases. We
also present in the current invention, 2-thioxothiazolidin-4-ones as antimicrobial and
antimalarial agents. We provide 2-thioxothiazolidin-4-ones as antimicrobial and antimalarial
agents either alone or in combination with other known antimicrobial and antimalarial
agents with or without added adjuvants or diluents or carriers.
2-thioxothiazolidin-4-one compounds and compositions as antimicrobial and antimalarial agents targeting enoyl-acp reductase of type II fatty acid synthesis pathway …
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