… to frailty and its change over 3 years. While the … change, especially over relatively short
intervals, would be of certain value. In our sample of the CLSA, the change in frailty over 3 years …

… change with increasing age and contribute to age … three genes and replicated our results
in a general population sample of 31 males and 29 females between 18 and 70 years of age…

… changes, improved risk indices for many age-related diseases, and a mean epigenetic age
approximately 1.5 years … relative changes of +9.6% (p > .3) and +12.4% (p > .2); Figure 3b). …

… age predictors (more commonly known as epigenetic clocks) are created using CpGs that
have tractable changes with age. The … In 2017, three mouse epigenetic clocks were developed …

… Here, we examined three classes of epigenetic age … changes in epigenetic age variables
between the second trimester and 1 year post-birth, and test associations between epigenetic …

… However, the important point remains that epigenetic age can change by > 3 years from
day to day in apparently healthy individuals without intervention. Although the short-term …

… accelerated epigenetic aging in the first 3 years of life (b = 0.40, p < 0.01), while infants with
birthweights ≥2500 g showed no significant change in epigenetic age acceleration (b = −…

… The potential reversibility of epigenetic changes may entail opportunities to alter the … Here,
we examined epigenetic age in 3 subgroups classified by differences in longitudinal episodic-…

… itself has its basis in epigenetic changes (including methylation changes) over time [6–9]. …
trial which assessed the effect of 2-3 years of daily supplementation with 400 mcg folic acid …

… genome that can lead to long-term changes in gene activity, consequently altering a biological
… We estimated the regression coefficients between epigenetic age acceleration measures …