581. The default mode network in Posttraumatic Stress Disorder (PTSD): A data-driven multimodal approach

T Akiki, C Averill, K Wrocklage… - Biological …, 2017 - biologicalpsychiatryjournal.com
Background The default mode network (DMN) has been increasingly demonstrated to play a
critical role in various brain functions. Alterations in DMN connectivity have been repeatedly
associated with psychopathology, including posttraumatic stress disorder (PTSD). However,
the network topology characteristics of DMN in PTSD have not been fully studied. Here we
implement a data-driven approach based on graph theory, to investigate the DMN in a group
of combat-exposed veterans. Methods Sixty-four veterans [PTSD: n= 34; combat control …
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