… and show that we can apply this technology to repress essential genes. Taking the results …
for efficient genetic repression in C. albicans, with important applications for genetic analysis …

… and show that we can apply this technology to repress essential genes. Taking the results …
for efficient genetic repression in C. albicans, with important applications for genetic analysis …

… platform that exploits a nuclease-dead version of the Cas9 … and enabling repression of
gene expression from a gene of … used to efficiently and specifically target essential genes for …

… CRISPR as a gene expression platform in Candida albicans using fusions between a Cas9
… the ability of the CRISPR interference (CRISPRi) system to repress gene expression in …

… that generate CRISPR interference (CRISPRi) or CRISPR … region of a gene via the sgRNA,
can repress or activate gene … CRISPRa platform for efficient genetic overexpression in C. …

… Since its initial applications in Candida albicans, CRISPR-Cas9 platforms are rapidly …
CRISPR variants were created to either repress or activate gene expression: CRISPR interference (…

… We create an inducible single plasmid CRISPRi system for gene repression in yeast, and
use it to … Here, we present a versatile platform for high-throughput characterization of CRISPR/…

… Therefore, this architecture, if efficient, would provide a more portable platform for swapping
out … Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions …

… Not all gRNAs will efficiently repress the expression of their target gene 22 . Therefore, we …
most effective gRNAs for a given gene. To this end, we sorted the gRNAs for each gene based …

… We demonstrate that the CRISPR-GRIT design with discrete transcriptional units can be
used for efficient multiplexed gene knockouts in C. albicans. Through sequencing, we elucidate …