A Canadian, multicentre study comparing the efficacy of a levonorgestrel-releasing intrauterine system to an oral contraceptive in women with idiopathic menorrhagia

J Endrikat, H Shapiro, E Lukkari-Lax, M Kunz… - Journal of Obstetrics and …, 2009 - Elsevier
Objectives To evaluate the efficacy of a levonorgestrel-releasing intrauterine system (LNG-
IUS) compared with a combined oral contraceptive containing 1 mg norethindrone acetate
and 20 μg ethinyl estradiol (OC1/20) in reducing menstrual blood loss (MBL) in women with
idiopathic menorrhagia. Methods A prospective, randomized, open-label study was
conducted in nine centres in Canada. Healthy women over 30 years of age suffering from
idiopathic menorrhagia were treated either with LNG-IUS (n= 20) or with OC1/20 (n= 19) …
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