A Quantitative, Multiparametric Method for Bone Edema and Adiposity Characterisation in Inflamed Trabecular Bone

TJP Bray, NS Sakai, A Dudek… - Proc Intl Soc Mag …, 2019 - archive.ismrm.org
MRI is increasingly used to identify and monitor inflammation in patients with inflammatory
diseases involving the skeleton, such as spondyloarthritis. However, conventional image
interpretation by radiologists provides only indirect information about the inflammatory
process and lacks reproducibility. Here, we describe a partially-automated multiparametric
MRI tool for quantifying and characterising both active and chronic inflammation in
spondyloarthritis, relying on histographic analysis of apparent diffusion coefficient (ADC) …
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