… HPV16 E6E7 and HRAS with or without exogenous MYC could confer tumor formation properties
on other human cell … Although, exogenous MYC expression resulted in the faster tumor-…

… that transduction of oncogenic HRAS (HRAS G12V ) and MYC together with HPV16 E6E7
is … -binding motif plays an important role in tumorigenic transformation of primary HCKs, and …

… with MYC overexpression play critical roles in transformation of … HRAS G12V and MYC
serially into HTK1-E6E7 cells and … combination of E6E7 and oncogenic HRAS without MYC can …

… E6 has been reported to act directly on cmyc, leading to … to play a key role as
rapamycininhibited cell growth in E6/E7 … HPV oncogenes E5, E6 and E7 play key roles in …

… of HPV16 E6 and E7, c-MYC (MYC), and oncogenic HRAS … The results highlighted an
important role of FOXA2 in the … HCK1T cells expressing E6E7 of HPV16 or HPV18, MYC T58A , …

… for malignant transformation. HPV-driven cancers share … important role for PIK3CA in
HPV-mediated carcinogenesis. … KRAS proto-oncogene, GTPase (KRAS) is an oncogene in …

… between transforming mitogenic signals and oncogenic … is crucial to allow the transition of
E6E7 keratinocytes from an … neck and cervical cancers, HRas plays an important role 9,10,11 . …

… full transformation of HCK on a background of HPV16 E6 and … that expression of oncogenic
Hras, ErbB2, or Myc can readily … of Hras and Myc to HCKs on the background of HPV16 E6E7 …

… , MYC and human papillomavirus 16 (HPV16) E6/E7 under … to fully transform the immortalized
HPDECs, and MYC markedly … Our PDAC model supports critical roles of KRAS mutations, …

… % of human cancers, are considered to play important roles in … ) and MYC together with
HPV16 E6E7 (E6E7) is enough to … of MYC are critical for transformation of human cells by E6E7 …