A general strategy for the synthesis of oxoisoindolo [2, 1-a] quinoline derivatives: the first efficient synthesis of 5, 6, 6a, 11-tetrahydro-11-oxoisoindolo [2, 1-a] quinoline …

AV Varlamov, FI Zubkov, EV Boltukhina, NV Sidorenko… - Tetrahedron letters, 2003 - Elsevier
… In the presence of p-toluensulfonic acid, 2,3-dihydro-3R-3-hydroxy-2-[2-(1-methylprop-1-enyl)phenyl]-1H-isoindol-1-ones
can be used to prepare either 6H-5-alkylidene-6,6a-dihydro-11-oxoisoindolo[2,1-a]quinolines
5 or 5-mono- and 5,6a-disubstituted isoindolo[2,1-a]quinoline-11(6aH)-ones. Condensation
of substituted … Continuing our investigations on the synthetic properties of
homoallyamines, we examined another possibility to prepare oxoisoindolo[2,1-a]quinolines
from these precursors. In this paper we describe a new synthesis of 5,5-dimethyl-11-oxoisoindolo[2,1-a]quinoline-10-carboxylic …
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