A lab-on-a-chip for cell detection and manipulation

G Medoro, N Manaresi, A Leonardi… - IEEE Sensors …, 2003 - ieeexplore.ieee.org
Presents a lab-on-a-chip for electronic manipulation and detection of microorganisms based
on the use of closed dielectrophoretic (DEP) cages combined with impedance sensing. A
printed circuit board (PCB) prototype has been used to trap, concentrate, and quantify
polystyrene micro-beads in agreement with CAD simulations. The experiment was
successfully repeated with S. cerevisiae. The results prove the effectiveness of the approach
for particle manipulation and detection without the need for external optical components nor …

A lab-on-a-chip for cell detection and manipulation

G Medoro, N Manaresi, A Leonardi… - SENSORS, 2002 …, 2002 - ieeexplore.ieee.org
This paper presents a lab-on-a-chip for electronic manipulation and detection of
microorganisms based on the use of closed dielectrophoretic (DEP) cages combined with
impedance sensing. A prototype has been realized using a standard printed circuit board
(PCB) technology by which polystyrene microbeads have been trapped, concentrated and
quantitated, in agreement with CAD simulations, without the need for external optical
components. The experiment was successfully repeated with S. cerevisiae. The approach is …
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