A molecular-dynamics study of lipid bilayers: effects of the hydrocarbon chain length on permeability
T Sugii, S Takagi, Y Matsumoto - The journal of chemical physics, 2005 - pubs.aip.org
In this paper, we investigate the effects of the hydrocarbon chain length of lipid molecules on
the permeation process of small molecules through lipid bilayers. We perform molecular-
dynamics simulations using three kinds of lipid molecules with different chain length:
dilauroylphosphatidylcholine, dimyristoylphosphatidylcholine, and
dipalmiltoylphosphatidylcholine. Free-energy profiles of O 2, CO, NO, and water molecules
are calculated by means of the cavity insertion Widom method and the probability ratio …
the permeation process of small molecules through lipid bilayers. We perform molecular-
dynamics simulations using three kinds of lipid molecules with different chain length:
dilauroylphosphatidylcholine, dimyristoylphosphatidylcholine, and
dipalmiltoylphosphatidylcholine. Free-energy profiles of O 2, CO, NO, and water molecules
are calculated by means of the cavity insertion Widom method and the probability ratio …
以上显示的是最相近的搜索结果。 查看全部搜索结果