BACKGROUND AND PURPOSE: Currently, inverse planning for intensity-modulated
radiotherapy (IMRT) can be a time-consuming trial and error process. This is because many
planning objectives are inherently contradictory and cannot reach their individual optimum
all at the same time. Therefore in clinical practice the potential of IMRT cannot be fully
exploited for all patients. Multicriteria (multiobjective) optimization combined with interactive
plan navigation is a promising approach to overcome these problems. PATIENTS AND …