A non-venomous sPLA2 of a lepidopteran insect: its physiological functions in development and immunity

M Vatanparast, S Ahmed, S Herrero, Y Kim - … & Comparative Immunology, 2018 - Elsevier
Eicosanoids are oxygenated C20 polyunsaturated fatty acids that mediate various
physiological processes in insects. Eicosanoid biosynthesis begins with a C20 precursor,
arachidonic acid (5, 8, 11, 14-eicosatetraenoic acid: AA). AA is usually released from
phospholipids at sn-2 position by catalytic activity of phospholipase A 2 (PLA 2). Although
various PLA 2 s classified into 16 gene families (= Groups) are known in various biological
systems, few PLA 2 s are known in insects. Only two PLA 2 s involved in intracellular calcium …
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