Oligodendroglioma poses a biological conundrum for malignant adult human gliomas: it is a
tumor type that is universally incurable for patients, and yet, only a few of the human tumors
have been established as cell populations in vitro or as intracranial xenografts in vivo. Their
survival, thus, may emerge only within a specific environmental context. To determine the
fate of human oligodendroglioma in an experimental model, we studied the development of
an anaplastic tumor after intracranial implantation into enhanced green fluorescent protein …

… A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with
mutations in FUBP1, CIC, and IDH1. … A novel, diffusely infiltrative xenograft model of
human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1. …