BACKGROUND Efficient bone regeneration using recombinant human bone morphogenetic
protein-2 (BMP-2) is needed to reduce side effects caused by high-dose BMP-2 use. The
composite material of polylactic acid–polyethene glycol (PLA-PEG) for sustained release
and an osteogenic nano-hydroxyapatite (nHAp) can contribute to efficient bone regeneration
by BMP-2. STUDY DESIGN An experimental in vitro and in vivo study. PURPOSE The
objective of this study is to investigate the effectiveness of a novel composite material of PLA …

CiNii 博士論文 - A novel nano-hydroxyapatite/synthetic polymer/bone morphogenetic protein-2
composite for efficient bone regeneration … A novel nano-hydroxyapatite/synthetic polymer/bone
morphogenetic protein-2 composite for efficient bone regeneration 有能な骨再生のために,ナノ
ハイドロクシアパタイト,PLA-PEG及びBMP-2を用いた新規複合体を作成すること … A novel nano-hydroxyapatite/synthetic
polymer/bone morphogenetic protein-2 composite for efficient bone regeneration …