The past decade has witnessed a paradigm shift in cancer therapy owing to the introduction
of immune checkpoint inhibitors (ICIs) and it is now commonplace for radiologists to image
patients on therapy with these agents. The purpose of this review is to detail the mechanism,
radiological manifestations and clinical significance of ICI related toxicities, according to the
organ system involved. ICI related toxicities that have known imaging manifestations include
colitis, enterocolitis, pancreatitis, hepatitis, endocrine toxicities, pneumonitis, cardiovascular …