A self-assembled AMF-responsive nanoplatform based on Pillar [5] arene and superparamagnetic nanoparticles for controlled release of doxorubicin

TS Fernandes, ECS Santos, VGC Madriaga… - Journal of the Brazilian …, 2019 - SciELO Brasil
An alternating magnetic field (AMF)-stimuli responsive nanodevice based on magnetic
nanoparticles (MNP) functionalized with water-soluble carboxylate-substituted pillar [5]
arene (CP [5] A), namely MNP-CP [5] A, as a multiplatform for cancer treatment has been
designed. MNP-CP [5] A was loaded with doxorubicin (DOX), showing a loading capacity of
9.5 mg g-1. The nanodevice demonstrated good colloidal stability, superparamagnetic
behavior, and was capable to generate detectable heat in solution induced by AMF …

A Self-Assembled AMF-Responsive Nanoplatform Based on Pillar [5] arene and Superparamagnetic Nanoparticles for Controlled Release of Doxorubicin

IAA Bessa, V Nascimento, F Garciab, CM Ronconi - SciELO Brasil
… Synthetic route employed to obtain water-soluble ammonium carboxylate-substituted
pillar[5]arene (CP[5]A). … ATR-FTIR spectra of acid pillar[5]arene (P[5]A) and the nanocarrier
MNP-CP[5]A. … TGA analysis of the nanocarrier MNP-CP[5]A and their precursors. …
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