Diabetes mellitus, often merely referred as diabetes, is a cluster of metabolic diseases in which a person blood sugar is raised, either because of the decreased secretion insulin, or decreased response of cells towards insulin that is produced. About 6% of the world population is affected by this chronic disease. Today, India is in prime position in the global diabetes epidemiological map as it is the home of nearly 33 million Diabetic subjects which is the highest number in the world. This is both, due to a rising prevalence of the disease and the large population in the country. It has been estimated that the global burden of type 2 diabetes mellitus (T2DM) for 2010 was 285 million people, which is projected to increase to 438 million in 2030; a 65% increase [1]. Similarly, for India this increase is estimated to be 58%, from 51 million people in 2010 to 87 million in 2030. The number of diabetes cases worldwide in the year 2000, among adults (< 20 years) was estimated to be 171 million and will rise to 366 million by 2030 [2]. Roughly 80% of people with diabetes are in developing countries, of which India and China share the massive contribution [3]. According to the World Health Organization (WHO) criteria, the prevalence of known diabetes is 5.6% and 2.7% among urban and rural areas in 2010, respectively [4].

Diabetes is managed pharmacologically by use of oral hypoglycemic agents and Insulin. The definite indications of insulin includes-All Type I Diabetes, Patients manifesting with failure to oral antidiabetic drugs, Pregnancy-if any medication is required for the control of glucose prenatally, Surgery: to control patient’s pre-operative, inter-operative, and post-operative conditions, hyperosmolar syndromes and other complication such as in renal failure or cardiac and liver disease, where anti diabetic medications cannot be used safely or adequately.