[HTML][HTML] A systematic evaluation of laboratory testing for drug‐induced immune thrombocytopenia

DM Arnold, S Kukaswadia, I Nazi, A Esmail… - Journal of Thrombosis …, 2013 - Elsevier
Background: Drug‐induced immune thrombocytopenia (DITP) can be confirmed by the
demonstration of drug‐dependent platelet antibodies in vitro; however, laboratory testing is
not readily accessible and test methods are not standardized. Objective: To identify drugs
with the strongest evidence for causing DITP based on clinical and laboratory criteria.
Patients/Methods: We developed a grading system to evaluate the quality of DITP laboratory
testing. The 'DITP criteria'were:(i) Drug (or metabolite) was required for the reaction in …
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