A targeted maximum likelihood estimator of a causal effect on a bounded continuous outcome

S Gruber, MJ van der Laan - The International Journal of Biostatistics, 2010 - degruyter.com
… the statistical counterpart of a causal parameter. In this article a new targeted maximum
likelihood estimator for estimating a causal effect of a binary treatment on a continuous outcome

Targeted maximum likelihood based causal inference: Part I

MJ van der Laan - The International Journal of Biostatistics, 2010 - degruyter.com
targeted maximum likelihood estimator of causal effects of … clinical outcome, and missingness
of the clinical outcome. … Lower bound for the variance of an unbiased estimator is maximal

A Targeted Maximum Likelihood Estimator of a Causal Effect on a Bounded Continuous Outcome

G Susan, J van der Laan Mark - The International Journal of …, 2010 - econpapers.repec.org
… into the estimate. We present an alternative targeted maximum likelihood estimation (TMLE)
approach that dampens the effect of these heavily weighted observations. As a substitution …

Targeted maximum likelihood estimation of natural direct effects

W Zheng, MJ Van Der Laan - The international journal of biostatistics, 2012 - degruyter.com
… define formally the natural direct causal effect of a binary treatment on an outcome using the
Non… has a version with a binary outcome Y and a version with a continuous and bounded

Targeted minimum loss based estimation of a causal effect on an outcome with known conditional bounds

S Gruber, MJ van der Laan - The international journal of biostatistics, 2012 - degruyter.com
… Doubly robust estimation in missing data and causal inference models. Biometrics, 61:962–…
targeted maximum likelihood estimator of a causal effect on a bounded continuous outcome. …

Targeted maximum likelihood estimation for causal inference in observational studies

MS Schuler, S Rose - American journal of epidemiology, 2017 - academic.oup.com
… applications of causal effect estimation use … outcome is bounded and continuous,
within the TMLE algorithm we transform Y to be bounded within (0, 1) and use a quasi-log-likelihood

tmle: an R package for targeted maximum likelihood estimation

S Gruber, M Van Der Laan - Journal of Statistical Software, 2012 - jstatsoft.org
… semi-parametric substitution estimator of a causal effect parameter or statistical association
log likelihood for binary outcomes is a valid loss function for continuous outcomes bounded

Targeted maximum likelihood learning

MJ Van Der Laan, D Rubin - The international journal of biostatistics, 2006 - degruyter.com
… of a marginal causal effect, and the parametric component in a … to hold if the log likelihood
of the data is uniformly boundedcausal effect of treatment A on the outcome Y . In this case, Ψ(…

An application of collaborative targeted maximum likelihood estimation in causal inference and genomics

S Gruber, MJ van der Laan - The International Journal of Biostatistics, 2010 - degruyter.com
… The outcome variable can either be continuous or binary. Assume we are interested in estimating
the marginal additive causal effect of treatment on the outcome. … -Rao efficiency bound. …

Bounded continuous outcomes

S Gruber, M van der Laan - Targeted Learning: Causal Inference for …, 2011 - Springer
… of the additive causal effect of a binary treatment on a bounded continuous outcome, which
… study we will use simple parametric maximum likelihood estimators as initial estimators Q0 …