ABCB1 c. 3435C> T polymorphism is associated with platinum toxicity: a preliminary study

…, S Ferrario, AR Gambaro, L Somma, C Fasola… - Cancer Chemotherapy …, 2019 - Springer
… In conclusion, the present study reveals that ABCB1 c.3435C>T polymorphism may
influence platinum toxicity. Variant T allele could exert a protective effect on the development of …

ABCB1 c.2677G>T/c.3435C>T diplotype increases the early-phase oral absorption of losartan

HB Shin, EH Jung, P Kang, CW Lim, KY Oh… - Archives of Pharmacal …, 2020 - Springer
3435C>T diplotypes of ABCB1 may significantly increase the early-phase absorption of
losartan, … In this study, the effects of major polymorphisms of the ABCB1 gene, c.2677G >T and c.…

Association between ABCB1 (MDR1) Gene 3435 C>T Polymorphism and Colchicine Unresponsiveness of FMF Patients

F Ozen, C Silan, A Uludag, F Candan, F Silan… - Renal failure, 2011 - Taylor & Francis
… ATP-binding cassette superfamily B member 1 (ABCB1 or MDR1, P-gly) is a drug transporter
that extrudes colchicine out of cells. C3435T polymorphism in ABCB1 gene has been …

[HTML][HTML] Polymorphism of the multidrug resistance 1 gene MDR1/ABCB1 C3435T and response to antiepileptic drug treatment in temporal lobe epilepsy

I Manna, A Gambardella, A Labate, L Mumoli… - Seizure, 2015 - Elsevier
… In the light of these controversial findings, the aim of the present study was to investigate
whether c.3435C>T polymorphism is more prevalent in patients with epilepsy versus control …

[HTML][HTML] Meta-analysis of ABCB1 3435C> T polymorphism and colorectal cancer

D Zhang, C Wang, Z Zhou - Pakistan Journal of Medical Sciences, 2013 - ncbi.nlm.nih.gov
… The pooled result of this meta-analysis indicated that the homozygous TT genotype of ABCB1
3435C>T polymorphism probably not affect CRC risk. We speculated that ABCB1 3435C>…

Haplotypes of ABCB1 1236C >T (rs1128503), 2677G >T/A (rs2032582), and 3435C >T (rs1045642) in patients with bullous pemphigoid

M Rychlik-Sych, M Barańska, M Dudarewicz… - Archives of …, 2018 - Springer
… (P-gp), the product of the ABCB1 gene. ABCB1 polymorphism might affect not only the …
In the present work, we resolved to conduct a haplotype analysis of ABCB1 in patients with …

[HTML][HTML] ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis

BS Haerian, H Roslan, AA Raymond, CT Tan, KS Lim… - Seizure, 2010 - Elsevier
C/T + T/T, assuming co-dominant, dominant, and recessive effects) of the 3435C allele
and the risk of resistance to AEDs. Deviation of Hardy–Weinberg equilibrium (HWE) was …

Frequency of ABCB1 gene 3435 polymorphism on patients with coronary stent in Surakarta

R Niruri, H Sulastomo, R Kusumati… - IOP Conference Series …, 2019 - iopscience.iop.org
ABCB1 3435 C>T is a silent single nucleotide polymorphism, but each allele that makes …
P-gp was encoded by ABCB1 gene. The 3435TT polymorphism was significantly associated …

ABCB1 haplotypes are associated with P‑gp activity and affect a major molecular response in chronic myeloid leukemia patients treated with a standard dose of …

D Vivona, LT Lima, AC Rodrigues… - Oncology …, 2014 - spandidos-publications.com
3435C>T and c.2677G>T/A polymorphisms markedly affect the secondary structure of ABCB1
… The aim of the present study was to investigate the influence of ABCB1 haplotypes on P‑…

Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P‐glycoprotein expression in human liver

A Owen, C Goldring, P Morgan… - British journal of …, 2005 - Wiley Online Library
… The aim of this study was to determine whether hepatic ABCB1 mRNA or P-gp expression
varied with the C 3435 T or the G 2677 T(A) SNPs. In our sample, the frequency of the C and T …