The main purpose of this study was to develop and apply an adaptive neuro-fuzzy inference system (ANFIS) and Artificial Neural Networks (ANNs) model for predicting the drying characteristics of potato, garlic and cantaloupe at convective hot air dryer. Drying experiments were conducted at the air temperatures of 40, 50, 60 and 70 °C and the air speeds of 0.5, 1 and l.5 m/s. Drying properties were including kinetic drying, effective moisture diffusivity (D_eff) and specific energy consumption (SEC). The highest value of D_eff obtained 9.76 × 10⁻⁹, 0.13 × 10⁻⁹ and 9.97 × 10⁻¹⁰ m²/s for potato, garlic, and cantaloupe, respectively. The lowest value of SEC for potato, garlic, and cantaloupe were calculated 1.94 × 10⁵, 4.52 × 10⁵ and 2.12 × 10⁵ kJ/kg, respectively. Results revealed that the ANFIS model had the high ability to predict the D_eff (R² = 0.9900), SEC (R² = 0.9917), moisture ratio (R² = 0.9974) and drying rate (R² = 0.9901) during drying. So ANFIS method had the high ability to evaluate all output as compared to ANNs method.