In this paper we present an adaptive per hop differentiation (APHD) scheme towards achieving end-to-end delay assurance in multihop wireless networks. Our APHD scheme extends the capability of IEEE 802.11e EDCA technique into multihop environments by taking end-to-end delay requirement into consideration. At an intermediate node, based on data packet's end-to-end requirement, its accumulative delay so far, and the current node's channel status, APHD smartly adjusts a data packet's priority level in order to satisfy its end-to-end delay requirement. Simulation results show that APHD scheme can provide excellent end-to-end delay assurance while achieving much higher network utilization, compared to a pure EDCA scheme