Abnormal Glucose Metabolism in Male Mice Offspring Conceived by in vitro Fertilization and Frozen-Thawed Embryo Transfer
N Qin, Z Zhou, W Zhao, K Zou, W Shi, C Yu… - Frontiers in Cell and …, 2021 - frontiersin.org
Frozen and thawed embryo transfer (FET) is currently widely applied in routine assisted
reproductive technology (ART) procedure. It is of great necessity to assess the safety of FET
and investigate the long-term effect including glucose metabolism on FET-conceived
offspring. The mouse model is a highly efficient method to figure out the relationship
between the process of FET and offspring health. In this study, we obtained mouse offspring
of natural conception (NC), in vitro fertilization (IVF), and FET. Glucose and insulin tolerance …
reproductive technology (ART) procedure. It is of great necessity to assess the safety of FET
and investigate the long-term effect including glucose metabolism on FET-conceived
offspring. The mouse model is a highly efficient method to figure out the relationship
between the process of FET and offspring health. In this study, we obtained mouse offspring
of natural conception (NC), in vitro fertilization (IVF), and FET. Glucose and insulin tolerance …
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